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Below is the list of Alchemy-related abilities in The Witcher 3: Wild Hunt:

Icon Name Description Prerequisite Levels Points
Brewing
This is one of your core Abilities. It is always active. Enables the brewing and drinking of witcher potions. None Default None
Heightened Tolerance
Level 1: Increases potion overdose threshold from 75% to 80%. Potion duration time: +5%.
Level 2: Increases potion overdose threshold from 75% to 85%. Potion duration time: +10%.
Level 3: Increases potion overdose threshold from 75% to 90%. Potion duration time: +15%.
Level 4: Increases potion overdose threshold from 75% to 95%. Potion duration time: +20%.
Level 5: Increases potion overdose threshold from 75% to 100%. Potion duration time: +25%.
Brewing 5 None
Refreshment
Level 1: Each potion dose imbibed heals 5% of maximum Vitality. Potion duration time: +5%
Level 2: Each potion dose imbibed heals 10% of maximum Vitality. Potion duration time: +10%
Level 3: Each potion dose imbibed heals 15% of maximum Vitality. Potion duration time: +15%
Level 4: Each potion dose imbibed heals 20% of maximum Vitality. Potion duration time: +20%
Level 5: Each potion dose imbibed heals 25% of maximum Vitality. Potion duration time: +25%
Brewing 5 8
Delayed Recovery
Potion effects don't wear off until potion Toxicity falls to 90% of the maximum level.
Potion duration time: +5%
Brewing 3 20
Side Effects
Imbibing a potion gives a 20% chance of activating the effects of another randomly-selected potion, without additional Toxicity cost.
Potion duration time: +5%
Brewing 5 28
Oil Preparation
This is one of your core Abilities. It is always active. Enables the creation of oils that can be applied to swords. None Default None
Poisoned Blades
The chance is greater the higher the level of oil used.
Level 1: Oil applied to blades gives a 3% chance of poisoning the target on each hit. Potion duration time: +5%.
Level 2: Oil applied to blades gives a 6% chance of poisoning the target on each hit. Potion duration time: +10%.
Level 3: Oil applied to blades gives a 9% chance of poisoning the target on each hit. Potion duration time: +15%.
Level 4: Oil applied to blades gives a 12% chance of poisoning the target on each hit. Potion duration time: +20%.
Level 5: Oil applied to blades gives a 15% chance of poisoning the target on each hit. Potion duration time: +25%.
Oil Preparation 5 None
Protective Coating
Level 1: Adds 5% protection against attacks from the monster type the oil targets. Potion duration time: +5%
Level 2: Adds 10% protection against attacks from the monster type the oil targets. Potion duration time: +10%
Level 3: Adds 15% protection against attacks from the monster type the oil targets. Potion duration time: +15%
Level 4: Adds 20% protection against attacks from the monster type the oil targets. Potion duration time: +20%
Level 5: Adds 25% protection against attacks from the monster type the oil targets. Potion duration time: +25%
Oil Preparation 5 8
Fixative
Level 1: Blade oils now have 33% more charges.
Potion duration time: +5%

Level 2: Blade oils now have 67% more charges.
Potion duration time: +10%

Level 3: Blade oils do not wear off.
Potion duration time: +15%

Oil Preparation 3 20
Hunter Instinct
When Adrenaline Points are at their maximum, critical hit damage against the targeted enemy type is increased by 20%.
Potion duration time: +5%
Oil Preparation 5 28
Bomb Creation
This is one of your core Abilities. It is always active. Enables the creation of handheld bombs that can be thrown at enemies. None Default None
Steady Aim
Time is slowed a further 15% while aiming bombs.
Potion duration time: +5%
Bomb Creation 3 None
Pyrotechnics
All bombs, even those that usually do not inflict damage now deal +30 damage in addition to their normal effects.
Potion duration time: +5%
Bomb Creation 5 8
Efficiency
Increases the maximum number of bombs in each slot by 1.
Potion duration time: +5%
Bomb Creation 5 20
Cluster Bombs
Upon detonation bombs separate into explosive fragments. Number of fragments: 2
Potion duration time: +5%
Bomb Creation 5 28
Mutation
This is one of your core Abilities. It is always active. Enables the extraction of mutagens from the corpses of powerful monsters. Witchers use these to grant their bodies new abilities. None Default None
Acquired Tolerance
Level 1: Every known level 1 alchemy formula increases maximum Toxicity by 1. Potion duration time: +5%.
Level 2: Every known level 1 or 2 alchemy formula increases maximum Toxicity by 1. Potion duration time: +10%.
Level 3: Every known level 1, 2 or 3 alchemy formula increases maximum Toxicity by 1. Potion duration time: +15%.
Mutation 3 None
Tissue Transmutation
When consumed, mutatgen decoction increases maximum Vitality by 200 for decoction's effective duration.
Potion duration time: +5%
Mutation 5 8
Synergy
Increases bonus for mutagen placed in mutagen slot by 10%.
Potion duration time: +5%
Mutation 5 20
Adaptation
Extends effective duration of all mutagen decoctions by 10%.
Potion duration time: +5%
Mutation 5 28
Trial of the Grasses
This is one of your core Abilities. It is always active. Mutation that lets witchers withstand the toxicity of potions that would kill normal people. None Default None
Frenzy
If potion Toxicity is above 0, time automatically slows when an enemy is about to perform a counterattack.
Level 1: Potion duration time: +5%
Level 2: The slowing effect and duration are greater than for level 1 of this ability. Potion duration time: +10%
Level 3: The slowing effect and duration are greater than for level 2 of this ability. Potion duration time: +15%
Trial of the Grasses 3 None
Endure Pain
Increases maximum Vitality by 10% when Toxicity exceeds the safe threshold.
Potion duration time: +5%
Trial of the Grasses 5 8
Fast Metabolism
Toxicity drops 1 point(s) per second faster.
Potion duration time: +5%
Trial of the Grasses 5 20
Killing Spree
If potion Toxicity is above 0, each opponent killed increases the chance for a critical hit by an additional 10% for the duration of that fight.
Potion duration time: +5%
Trial of the Grasses 5 28